Name: HOTEL ISLA GRANDE
Rating: 4.8

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Your Eastern Panama Vacation

Leave all the planning to us with an Eastern Panama vacation package. With everything organized before you jet off, all you need to do is sit back, chill out and experience this destination's many wonders. Where to start your journey? In the most popular cities, of course. Isla Tigre and Palenque are two great places to kick off your itinerary during your trip to Eastern Panama. When it's time to stop daydreaming and start doing, Expedia will help turn your Eastern Panama vacation into reality.

The Latest Eastern Panama vacation packages

Price found within the past 48 hours. Click for updated prices.

Mahogany Suites

$730

per person

May 13 - May 20

found 1 day ago

Roundtrip flight included

Newark Liberty Intl. Airport (EWR) to Panama City (PTY)

9.2/10 Wonderful! (5 reviews)

Great place to stay. Comfortable, clean, nice grounds with lots of walking paths. Very safe and there is a restaurant on the property, pool, gym and other great amenities. Excellent stay. My only word of advice is to make sure you have your reservation details ready when you arrive at the security gate. This is a gated community. We were given the apartment keys at the security gate. It wasn’t clear in the instructions after booking. But don’t let that stop you. We plan on staying here again.

Reviewed on Mar 11, 2026

Hotel Riu Plaza Panama

Bella Vista

Save 100% on your flight

$813

per person

Apr 24 - May 1

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

9/10 Wonderful! (5,057 reviews)

The only thing preventing a 5-star review is that towels were removed from my room, and also from a friend’s room in a totally different floor. We arrived tired from the day and couldn’t take a shower for almost an hour and after 5 calls to the front desk. Other than that l, everything was great. Breakfast, amenities, response to requests… will definitely stay there again if I return to Panama!

Reviewed on Mar 12, 2026

Central Hotel Panama Casco Viejo

Casco Viejo

Save 100% on your flight

$1,481

per person

Apr 27 - May 4

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

9/10 Wonderful! (1,010 reviews)

Great location clean safe and walkable!! Wonderful hotel

Reviewed on Mar 10, 2026

Megapolis Hotel Panamá

San Francisco

$1,203

per person

Apr 27 - May 4

found 1 day ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

8.4/10 Very Good! (1,441 reviews)

The room are nice and clean the pool is too much noise. It’s a mess

Reviewed on Mar 10, 2026

Lesplanade by Wynwood House

El Chorrillo

$1,060

per person

Apr 27 - May 4

found 16 hours ago

Roundtrip flight included

Bridgetown (BGI) to Panama City (PTY)

6/10 (3 reviews)

This was a great location in Casco Viejo. Close to grocery, restaurants, bars. Very walkable. Close to the malecon for jogging / walking. Rooftop pool and deck perfect for sunrise / sunset. Unit had everything we needed. Only negative was we asked for an extra blanket and were told that was not available.

Reviewed on Jan 6, 2025

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Discover the most popular places to visit in Eastern Panama

Museum of the Kuna Nation

You can spend an afternoon studying the exhibits at Museum of the Kuna Nation in Narganá. Stroll along the seaside or experience the area's festivals.

Porvenir Museum

You can spend time browsing the exhibits at Porvenir Museum during your travels in Narganá. Amble around the area's seaside or experience its festivals.

Eastern Panama Hotel Deals

Hotel Cocotal

La Guaira Isla Grande Provincia de Colón

Fully refundableReserve now, pay when you stay

$95 nightly

$105 total

Mar 15 - Mar 16

Total with taxes and fees

Ordovician Beach Resort

Isla Grande Isla Grande Colon

$440 nightly

$490 total

Mar 20 - Mar 21

Total with taxes and fees

10/10 Exceptional! (9 reviews)

The resort was outstanding. It exceeded expectations in every way. The service was the best we had in Panama. The cocktails were fun and the food was delicious and they have a vegan menu. We stayed in a king room and it was very private, pristine and well appointed.

Reviewed on Feb 21, 2026

HOTEL ISLA GRANDE

Final de paseo La Punta Isla Grande, 01 Isla Grande Colón Province

4.8/10 (8 reviews)

This hotel is very run down, and should not be $150/night. Did not have access to running water in our room. Location and beach are its saving graces.

Reviewed on Feb 4, 2026

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See all 177 properties in Eastern Panama

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.